PNASPD1和FoxP3在新型自 - 问答 - 胆源性胰腺炎胆源性胰腺炎

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发送短消息 UID 222 精华 0 查看公共资料搜索主题搜索帖子 TUhjnbcbe TUhjnbcbe 组别新手上路生日帖子1 积分12 性别注册时间2020-03-27	1^# 字体大小: t T 发表于 2021-01-25 03:28 \|只看楼主合肥较好的白癜风医院 http://m.39.net/pf/a_6171967.html paperreading NonoverlappingrolesofPD-1andFoxP3inmaintainingimmunetoleranceinanovelautoimmunepancreatitismousemodel BaihaoZhang.etal. PNAS, ForhumansormiceFoxp3+TregcellsconstitutivelyexpressPD-1underdiversecondition,theauthorswanttoknowtheprecisefunctionofPD-1inFoxp3+Tregcells.Thus,theycrossedPD-1KOmicewithFoxp3-GFPcremicewhichcarriedtheIRES-GFPcrereporterKIatthe3’untranslatedregionoftheFoxp3gene.LossofPD-1inFoxp3-GFPcreKI/YandFoxp3-GFPcreKI/KImiceincurreddeathintheirearlyagesandtheyalsofoundthatFoxp3expressionisreducedinFoxp3-GFPcremice
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PNASPD1和FoxP3在新型自 [复制链接]